Title : The nucleoside triphosphatase and helicase activities of vaccinia virus NPH-II are essential for virus replication.

Pub. Date : 1998 Jun

PMID : 9573237






1 Functional Relationships(s)
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1 These findings, together with previous mutational studies, indicate that NPH-II motifs I, Ia, II, and VI (QRxGRxGRxxxG) are essential for nucleoside triphosphate (NTP) hydrolysis, whereas motif III and the His moiety of the DExH-box serve to couple the NTPase and helicase activities. ntp inosine triphosphatase Homo sapiens