Protein Name retinoic acid receptor beta
Organism Homo sapiens
Gene ID 5915
Gene Symbol

RARB

UniProt P10826 (RARB_HUMAN), F1D8S6 (F1D8S6_HUMAN), Q5QHG3 (Q5QHG3_HUMAN), Q86UC5 (Q86UC5_HUMAN), Q3SB16 (Q3SB16_HUMAN)
Relationships Total Number of functionally related compound(s) : 278
Total Number of Articles : 495
Description

retinoic acid receptor beta

Gene Summary

This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014]

synonyms
  • retinoic acid receptor beta
  • HBV-activated protein
  • RAR-beta
Click to show/hide the synonyms
Properties