Pub. Date : 1997 Apr
PMID : 9083277
13 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prostaglandin E2 stimulates expression of matrix metalloproteinase 2 in cultured rat mesangial cells. | Dinoprostone | matrix metallopeptidase 2 | Rattus norvegicus |
| 2 | PGE2 increased MMP-2 mRNA levels beginning at one hour of incubation and remained elevated up to 24 hours. | Dinoprostone | matrix metallopeptidase 2 | Rattus norvegicus |
| 3 | Nuclear run off experiments revealed that the PGE2-induced increase in mRNA expression for MMP-2 is due to stimulated gene transcription. | Dinoprostone | matrix metallopeptidase 2 | Rattus norvegicus |
| 4 | Western blot analysis and zymography revealed that MMP-2 protein production and enzyme activity was also enhanced by PGE2. | Dinoprostone | matrix metallopeptidase 2 | Rattus norvegicus |
| 5 | The cAMP analogue 8-bromo-cAMP increased MMP-2 mRNA levels, suggesting that PGE2-induced generation of intracellular cAMP plays a role in MMP-2 induction in MC. | Cyclic AMP | matrix metallopeptidase 2 | Rattus norvegicus |
| 6 | The cAMP analogue 8-bromo-cAMP increased MMP-2 mRNA levels, suggesting that PGE2-induced generation of intracellular cAMP plays a role in MMP-2 induction in MC. | Cyclic AMP | matrix metallopeptidase 2 | Rattus norvegicus |
| 7 | The cAMP analogue 8-bromo-cAMP increased MMP-2 mRNA levels, suggesting that PGE2-induced generation of intracellular cAMP plays a role in MMP-2 induction in MC. | 8-Bromo Cyclic Adenosine Monophosphate | matrix metallopeptidase 2 | Rattus norvegicus |
| 8 | The cAMP analogue 8-bromo-cAMP increased MMP-2 mRNA levels, suggesting that PGE2-induced generation of intracellular cAMP plays a role in MMP-2 induction in MC. | 8-Bromo Cyclic Adenosine Monophosphate | matrix metallopeptidase 2 | Rattus norvegicus |
| 9 | The cAMP analogue 8-bromo-cAMP increased MMP-2 mRNA levels, suggesting that PGE2-induced generation of intracellular cAMP plays a role in MMP-2 induction in MC. | Dinoprostone | matrix metallopeptidase 2 | Rattus norvegicus |
| 10 | The cAMP analogue 8-bromo-cAMP increased MMP-2 mRNA levels, suggesting that PGE2-induced generation of intracellular cAMP plays a role in MMP-2 induction in MC. | Dinoprostone | matrix metallopeptidase 2 | Rattus norvegicus |
| 11 | The cAMP analogue 8-bromo-cAMP increased MMP-2 mRNA levels, suggesting that PGE2-induced generation of intracellular cAMP plays a role in MMP-2 induction in MC. | Cyclic AMP | matrix metallopeptidase 2 | Rattus norvegicus |
| 12 | The cAMP analogue 8-bromo-cAMP increased MMP-2 mRNA levels, suggesting that PGE2-induced generation of intracellular cAMP plays a role in MMP-2 induction in MC. | Cyclic AMP | matrix metallopeptidase 2 | Rattus norvegicus |
| 13 | These studies demonstrate that PGE2 stimulates the transcription, protein formation and enzyme activity of MMP-2 in cultured rat MC. | Dinoprostone | matrix metallopeptidase 2 | Rattus norvegicus |