Title : IL-2 induces beta2-integrin adhesion via a wortmannin/LY294002-sensitive, rapamycin-resistant pathway. Phosphorylation of a 125-kilodalton protein correlates with induction of adhesion, but not mitogenesis.

Pub. Date : 1996 Dec 15

PMID : 8955182






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Wortmannin, LY294002, and cytochalasin E almost completely inhibit cytokine-induced tyrosine phosphorylation of p125, whereas tyrosine phosphorylation of PI-3 kinase, Janus kinases, Stat3, Stat5, and other proteins is unaffected. Wortmannin signal transducer and activator of transcription 5A Homo sapiens
2 Wortmannin, LY294002, and cytochalasin E almost completely inhibit cytokine-induced tyrosine phosphorylation of p125, whereas tyrosine phosphorylation of PI-3 kinase, Janus kinases, Stat3, Stat5, and other proteins is unaffected. 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one signal transducer and activator of transcription 5A Homo sapiens
3 Wortmannin, LY294002, and cytochalasin E almost completely inhibit cytokine-induced tyrosine phosphorylation of p125, whereas tyrosine phosphorylation of PI-3 kinase, Janus kinases, Stat3, Stat5, and other proteins is unaffected. cytochalasin E signal transducer and activator of transcription 5A Homo sapiens