Title : Function and localization of cytochromes P450 involved in the metabolic activation of food-derived heterocyclic amines.

Pub. Date : 1995

PMID : 8844805






6 Functional Relationships(s)
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1 Members of the human CYP3A subfamily (CYP3A4 and CYP3A5) were capable of activating the heterocyclic amine, 2-amino-3,4-dimethylimadazo[4,5,f]quinoline (MeIQ), to a mutagen in the Ames test in the presence of the modulating flavonoid, alpha-napthoflavone. heterocyclic cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 Members of the human CYP3A subfamily (CYP3A4 and CYP3A5) were capable of activating the heterocyclic amine, 2-amino-3,4-dimethylimadazo[4,5,f]quinoline (MeIQ), to a mutagen in the Ames test in the presence of the modulating flavonoid, alpha-napthoflavone. Amines cytochrome P450 family 3 subfamily A member 5 Homo sapiens
3 Members of the human CYP3A subfamily (CYP3A4 and CYP3A5) were capable of activating the heterocyclic amine, 2-amino-3,4-dimethylimadazo[4,5,f]quinoline (MeIQ), to a mutagen in the Ames test in the presence of the modulating flavonoid, alpha-napthoflavone. 2-amino-3,4-dimethylimadazo[4,5,f]quinoline cytochrome P450 family 3 subfamily A member 5 Homo sapiens
4 Members of the human CYP3A subfamily (CYP3A4 and CYP3A5) were capable of activating the heterocyclic amine, 2-amino-3,4-dimethylimadazo[4,5,f]quinoline (MeIQ), to a mutagen in the Ames test in the presence of the modulating flavonoid, alpha-napthoflavone. 2-amino-3,4-dimethylimidazo(4,5-f)quinoline cytochrome P450 family 3 subfamily A member 5 Homo sapiens
5 Members of the human CYP3A subfamily (CYP3A4 and CYP3A5) were capable of activating the heterocyclic amine, 2-amino-3,4-dimethylimadazo[4,5,f]quinoline (MeIQ), to a mutagen in the Ames test in the presence of the modulating flavonoid, alpha-napthoflavone. Flavonoids cytochrome P450 family 3 subfamily A member 5 Homo sapiens
6 Members of the human CYP3A subfamily (CYP3A4 and CYP3A5) were capable of activating the heterocyclic amine, 2-amino-3,4-dimethylimadazo[4,5,f]quinoline (MeIQ), to a mutagen in the Ames test in the presence of the modulating flavonoid, alpha-napthoflavone. alpha-napthoflavone cytochrome P450 family 3 subfamily A member 5 Homo sapiens