Pub. Date : 1996 Feb
PMID : 8742240
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | There are now a number of substrates reported that have routes of metabolism ascribed specifically to cytochrome P4502C9 (CYP2C9), the isoform mainly responsible for tolbutamide hydroxylation. | Tolbutamide | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | There are now a number of substrates reported that have routes of metabolism ascribed specifically to cytochrome P4502C9 (CYP2C9), the isoform mainly responsible for tolbutamide hydroxylation. | Tolbutamide | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 3 | The substrate specificity has been rationalized in terms of a hydrogen bond donor/acceptor model and, by use of molecular modeling, an active site template model for CYP2C9 has been generated. | Hydrogen | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |