Title : Tax induces nuclear translocation of NF-kappa B through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of I kappa B alpha/MAD3.

Pub. Date : 1994 Dec

PMID : 7966593






2 Functional Relationships(s)
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1 Treatment of cells with classical NF-kappa B inducers such as tumor necrosis factor, interleukin-1, phorbol myristate acetate, and lipopolysaccharide results in MAD3 degradation followed by nuclear translocation of NF-kappa B. Tetradecanoylphorbol Acetate NFKB inhibitor alpha Homo sapiens
2 On the other hand, Tax induces no apparent degradation of MAD3, although experiments using cycloheximide indicate that it decreases the half-life of MAD3. Cycloheximide NFKB inhibitor alpha Homo sapiens