PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7929400-1 1994 5-Lipoxygenase is the first committed enzyme in the leukotriene biosynthetic pathway and is known to catalyze not only the first oxygenation of arachidonate to form 5(S)-hydroperoxyeicosatetraenoic acid (5(S)-HPETE), but also dehydration of this intermediate into leukotriene A4 (LTA4) by an activity termed leukotriene A4 synthase. Leukotriene A4 264-278 arachidonate 5-lipoxygenase Homo sapiens 0-14 7929400-1 1994 5-Lipoxygenase is the first committed enzyme in the leukotriene biosynthetic pathway and is known to catalyze not only the first oxygenation of arachidonate to form 5(S)-hydroperoxyeicosatetraenoic acid (5(S)-HPETE), but also dehydration of this intermediate into leukotriene A4 (LTA4) by an activity termed leukotriene A4 synthase. Leukotriene A4 264-278 arachidonate 5-lipoxygenase Homo sapiens 308-331