Title : Function of wild-type or mutant Rac2 and Rap1a GTPases in differentiated HL60 cell NADPH oxidase activation.

Pub. Date : 1995 Feb 1

PMID : 7833480






2 Functional Relationships(s)
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1 Studies of neutrophil nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation in a cell-free system showed that the low molecular-weight guanosine triphosphatase (GTPase) Rac was required, and that Rap1a may participate in activation of the catalytic complex. Adenine Rac family small GTPase 2 Homo sapiens
2 In the present studies, oligonucleotide-directed mutagenesis was used to introduce a series of mutations into human rap1a or rac2 in the mammalian expression vector pSR alpha neo. Oligonucleotides Rac family small GTPase 2 Homo sapiens