Protein Name Rac family small GTPase 2
Organism Homo sapiens
Gene ID 5880
Gene Symbol


UniProt P15153 (RAC2_HUMAN), A0A024R1P2 (A0A024R1P2_HUMAN), V9H0H7 (V9H0H7_HUMAN)
Relationships Total Number of functionally related compound(s) : 197
Total Number of Articles : 191

Rac family small GTPase 2

Gene Summary

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]

  • ras-related C3 botulinum toxin substrate 2
  • Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2)
  • ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
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