Title : Chemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound.

Pub. Date : 1995 Jan 15

PMID : 7812955






3 Functional Relationships(s)
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1 The present study was designed to investigate the chemopreventive action of dietary curcumin on azoxymethane-induced colon carcinogenesis and also the modulating effect of this agent on the colonic mucosal and tumor phospholipase A2, phospholipase C gamma 1, lipoxygenase, and cyclooxygenase activities in male F344 rats. Curcumin phospholipase C gamma 1 Homo sapiens
2 Animals fed the curcumin diet showed decreased activities of colonic mucosal and tumor phospholipase A2 (50%) and phospholipase C gamma 1 (40%) and levels of PGE2 (> 38%). Curcumin phospholipase A2 group IB Homo sapiens
3 Animals fed the curcumin diet showed decreased activities of colonic mucosal and tumor phospholipase A2 (50%) and phospholipase C gamma 1 (40%) and levels of PGE2 (> 38%). Curcumin phospholipase C gamma 1 Homo sapiens