Pub. Date : 1983 Sep
PMID : 6417475
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In both PWM-stimulated (for 2 days) and unstimulated PBL, equal proportions of free and disulfide-linked J-chain were found. | Disulfides | joining chain of multimeric IgA and IgM | Homo sapiens |
| 2 | In tissue culture fluids, J-chain was not secreted in a free form but was always disulfide-linked to polymeric Igs. | Disulfides | joining chain of multimeric IgA and IgM | Homo sapiens |
| 3 | In lymphoblastoid cell lines, J-chain was present in a disulfide-linked form in IgM and IGA producers, but in IgG cells and in an IgM cell line (DAUDI) that did not secrete IgM but expressed it on the cell membrane, intracellular J-chain was present in free form. | Disulfides | joining chain of multimeric IgA and IgM | Homo sapiens |
| 4 | Further studies revealed that the ability to produce polymers was not equally distributed among all cells and might vary according to their content of J-chain and stage of maturation. | Polymers | joining chain of multimeric IgA and IgM | Homo sapiens |
| 5 | In lysates of IgG and J-chain producing cells grown in the presence of 3H-labeled amino acids, intracellular J-chain was not disulfide-linked to IgG. | Tritium | joining chain of multimeric IgA and IgM | Homo sapiens |
| 6 | In lysates of IgG and J-chain producing cells grown in the presence of 3H-labeled amino acids, intracellular J-chain was not disulfide-linked to IgG. | Tritium | joining chain of multimeric IgA and IgM | Homo sapiens |