Protein Name joining chain of multimeric IgA and IgM
Organism Homo sapiens
Gene ID 3512
Gene Symbol

JCHAIN

UniProt P01591 (IGJ_HUMAN)
Relationships Total Number of functionally related compound(s) : 73
Total Number of Articles : 66
Description

joining chain of multimeric IgA and IgM

Gene Summary

Enables IgA binding activity and protein homodimerization activity. Contributes to several functions, including immunoglobulin receptor binding activity; peptidoglycan binding activity; and phosphatidylcholine binding activity. Involved in several processes, including glomerular filtration; innate immune response; and positive regulation of respiratory burst. Located in extracellular space. Part of monomeric IgA immunoglobulin complex; pentameric IgM immunoglobulin complex; and secretory dimeric IgA immunoglobulin complex. [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • immunoglobulin J chain
  • IgJ chain
  • J chain
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Properties