Pub. Date : 2021 Aug 29
PMID : 34564613
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of (-)-Epigallocatechin Gallate on Activation of JAK/STAT Signaling Pathway by Staphylococcal Enterotoxin A. Staphylococcal enterotoxin A (SEA), which is a superantigen toxin protein, binds to cytokine receptor gp130. | epigallocatechin gallate | interleukin 6 signal transducer | Mus musculus |
| 2 | Through protein thermal shift assay in vitro, the binding of the gp130 receptor to SEA and the phosphorylation of STAT3 were inhibited by the interaction between EGCG and SEA. | epigallocatechin gallate | interleukin 6 signal transducer | Mus musculus |
| 3 | As far as we know, this is the first report to document that EGCG inhibits the binding of the gp130 receptor to SEA and the associated phosphorylation of STAT3. | epigallocatechin gallate | interleukin 6 signal transducer | Mus musculus |