Title : The multi-target mechanism of Cyclosporin A in the treatment of vitiligo based on network pharmacology.

Pub. Date : 2021 Jul

PMID : 34089287






2 Functional Relationships(s)
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1 Through screening and molecular docking, PRKDC, CUL7, CUL1, HSPA8, HSPA4 and SIRT7 were the most likely multi-target mechanism of Cyclosporin A in the treatment of vitiligo. Cyclosporine sirtuin 7 Homo sapiens
2 In addition, Cyclosporin A might promote the repigmentation of vitiligo by adjusting the expression of SIRT7. Cyclosporine sirtuin 7 Homo sapiens