Title : MicroRNA-155-5p/EPAS1/interleukin 6 pathway participated in the protection function of sphingosylphosphorylcholine to ischemic cardiomyocytes.

Pub. Date : 2021 Jan 1

PMID : 33130081






2 Functional Relationships(s)
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1 MicroRNA-155-5p/EPAS1/interleukin 6 pathway participated in the protection function of sphingosylphosphorylcholine to ischemic cardiomyocytes. sphingosine phosphorylcholine endothelial PAS domain protein 1 Rattus norvegicus
2 EPAS1 levels did not change when its transcript was blocked by Actinomycin D, which prompted us to search for a post-transcription mechanism for its increased expression, and finally found that miR-155-5p, regulated by STAT3, was a new post-transcription regulator to EPAS1. Dactinomycin endothelial PAS domain protein 1 Rattus norvegicus