Title : Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-κB and HO-1 signaling pathways in mice.

Pub. Date : 2020 Dec

PMID : 33039967






12 Functional Relationships(s)
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1 Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-kappaB and HO-1 signaling pathways in mice. alpinetin thymoma viral proto-oncogene 1 Mus musculus
2 Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-kappaB and HO-1 signaling pathways in mice. alpinetin nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
3 Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-kappaB and HO-1 signaling pathways in mice. alpinetin heme oxygenase 1 Mus musculus
4 Alpinetin also decreased the OVA-induced levels of IL-4, IL-5, IL-13 and IgE. alpinetin interleukin 4 Mus musculus
5 Alpinetin also decreased the OVA-induced levels of IL-4, IL-5, IL-13 and IgE. alpinetin interleukin 5 Mus musculus
6 Alpinetin also decreased the OVA-induced levels of IL-4, IL-5, IL-13 and IgE. alpinetin interleukin 13 Mus musculus
7 Furthermore, alpinetin inhibited OVA-induced phosphorylation of p65, IkappaB, PI3K and AKT, and the activity of HO-1 in vivo. alpinetin v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus
8 Furthermore, alpinetin inhibited OVA-induced phosphorylation of p65, IkappaB, PI3K and AKT, and the activity of HO-1 in vivo. alpinetin thymoma viral proto-oncogene 1 Mus musculus
9 Furthermore, alpinetin inhibited OVA-induced phosphorylation of p65, IkappaB, PI3K and AKT, and the activity of HO-1 in vivo. alpinetin heme oxygenase 1 Mus musculus
10 In conclusion, above results indicate that alpinetin exhibites a potent anti-inflammatory activity in allergic asthma through modulating PI3K/AKT/NF-kappaB and HO-1 signaling pathways, which would be used as a promising therapy agent for allergic asthma. alpinetin thymoma viral proto-oncogene 1 Mus musculus
11 In conclusion, above results indicate that alpinetin exhibites a potent anti-inflammatory activity in allergic asthma through modulating PI3K/AKT/NF-kappaB and HO-1 signaling pathways, which would be used as a promising therapy agent for allergic asthma. alpinetin nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
12 In conclusion, above results indicate that alpinetin exhibites a potent anti-inflammatory activity in allergic asthma through modulating PI3K/AKT/NF-kappaB and HO-1 signaling pathways, which would be used as a promising therapy agent for allergic asthma. alpinetin heme oxygenase 1 Mus musculus