Pub. Date : 2019 Feb 1
PMID : 30578034
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclic tripeptide-based potent human SIRT7 inhibitors. | cyclic tripeptide | sirtuin 7 | Homo sapiens |
| 2 | In the current study, two cyclic tripeptides respectively harboring a thiourea-type and a carboxamide-type of catalytic mechanism-based sirtuin inhibitory warheads as the central residue were found to behave as potent (low muM level) inhibitors against the tRNA-activated human SIRT7 deacetylase activity. | cyclic tripeptides | sirtuin 7 | Homo sapiens |