Title : COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways.

Pub. Date : 2018 Nov 2

PMID : 30239896






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 STX5 can re-locate to LEs upon PS-ASO incubation, can bind PS-ASOs, and the binding appears to be required for this pathway. Phosphorus syntaxin 5 Homo sapiens
2 STX5 can re-locate to LEs upon PS-ASO incubation, can bind PS-ASOs, and the binding appears to be required for this pathway. ps-asos syntaxin 5 Homo sapiens
3 Our study reveals a novel release pathway in which PS-ASO incubation causes LE re-localization of STX5, which mediates the recruitment of COPII vesicles to LEs to facilitate endosomal PS-ASO release, and identifies another key PS-ASO binding protein. ps-aso syntaxin 5 Homo sapiens
4 Our study reveals a novel release pathway in which PS-ASO incubation causes LE re-localization of STX5, which mediates the recruitment of COPII vesicles to LEs to facilitate endosomal PS-ASO release, and identifies another key PS-ASO binding protein. ps-aso syntaxin 5 Homo sapiens
5 Our study reveals a novel release pathway in which PS-ASO incubation causes LE re-localization of STX5, which mediates the recruitment of COPII vesicles to LEs to facilitate endosomal PS-ASO release, and identifies another key PS-ASO binding protein. Phosphorus syntaxin 5 Homo sapiens