PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29231244-7 2018 Meanwhile, SIRT7 depletion can increase the sensitivity of breast cancer cells to doxorubicin (DOX). Doxorubicin 82-93 sirtuin 7 Homo sapiens 11-16 29231244-7 2018 Meanwhile, SIRT7 depletion can increase the sensitivity of breast cancer cells to doxorubicin (DOX). Doxorubicin 95-98 sirtuin 7 Homo sapiens 11-16 29231244-8 2018 Xenograft model studies showed that stable silencing of SIRT7 inhibited tumor growth and enhanced tumor sensitivity to DOX. Doxorubicin 119-122 sirtuin 7 Homo sapiens 56-61 29231244-10 2018 Taken together, our results showed that SIRT7 plays a critical role in breast cancer cell survival, migration, and tumor growth, and increased the efficiency of DOX treatment both in vitro and in vivo. Doxorubicin 161-164 sirtuin 7 Homo sapiens 40-45