Title : Hinokitiol suppresses cancer stemness and oncogenicity in glioma stem cells by Nrf2 regulation.

Pub. Date : 2017 Aug

PMID : 28685346






3 Functional Relationships(s)
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1 RESULTS: We demonstrated that hinokitiol effectively inhibited the CD133 positivity and ALDH1 activity along with the reduced self-renewal, migration, invasion, and colony formation properties of GSCs. beta-thujaplicin prominin 1 Homo sapiens
2 RESULTS: We demonstrated that hinokitiol effectively inhibited the CD133 positivity and ALDH1 activity along with the reduced self-renewal, migration, invasion, and colony formation properties of GSCs. beta-thujaplicin aldehyde dehydrogenase 1 family member A1 Homo sapiens
3 Furthermore, we showed that administration of exogenous Nrf2 counteracted the inhibitory effect of hinokitiol on self-renewal and invasiveness of GSCs. beta-thujaplicin NFE2 like bZIP transcription factor 2 Homo sapiens