Pub. Date : 2016 Aug
PMID : 27387722
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Crude (phenol extracted) lipopolysaccharide (cLPS), which often contains other immunostimulatory molecules, including NOD1 agonist, is known to induce almost the whole bacterial response. | cryptolepine | nucleotide binding oligomerization domain containing 1 | Bos taurus |
| 2 | This study was conducted to explore the role of NOD1/nuclear factor (NF)-kappaB pathway in the cytokine and functional responses of bovine neutrophils challenged with Escherichia coli-derived cLPS. | cryptolepine | nucleotide binding oligomerization domain containing 1 | Bos taurus |
| 3 | Cells were then exposed to cLPS for additional 4 h. Inhibition of the NOD1/NF-kappaB pathway resulted in a decrease in cLPS-induced phosphorylation of the inhibitor of NF-kappaBalpha (IkappaBalpha) in neutrophils. | cryptolepine | nucleotide binding oligomerization domain containing 1 | Bos taurus |
| 4 | Cells were then exposed to cLPS for additional 4 h. Inhibition of the NOD1/NF-kappaB pathway resulted in a decrease in cLPS-induced phosphorylation of the inhibitor of NF-kappaBalpha (IkappaBalpha) in neutrophils. | cryptolepine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 5 | Cells were then exposed to cLPS for additional 4 h. Inhibition of the NOD1/NF-kappaB pathway resulted in a decrease in cLPS-induced phosphorylation of the inhibitor of NF-kappaBalpha (IkappaBalpha) in neutrophils. | cryptolepine | NFKB inhibitor alpha | Bos taurus |
| 6 | Cells were then exposed to cLPS for additional 4 h. Inhibition of the NOD1/NF-kappaB pathway resulted in a decrease in cLPS-induced phosphorylation of the inhibitor of NF-kappaBalpha (IkappaBalpha) in neutrophils. | cryptolepine | nucleotide binding oligomerization domain containing 1 | Bos taurus |
| 7 | Cells were then exposed to cLPS for additional 4 h. Inhibition of the NOD1/NF-kappaB pathway resulted in a decrease in cLPS-induced phosphorylation of the inhibitor of NF-kappaBalpha (IkappaBalpha) in neutrophils. | cryptolepine | nuclear factor kappa B subunit 1 | Homo sapiens |
| 8 | Cells were then exposed to cLPS for additional 4 h. Inhibition of the NOD1/NF-kappaB pathway resulted in a decrease in cLPS-induced phosphorylation of the inhibitor of NF-kappaBalpha (IkappaBalpha) in neutrophils. | cryptolepine | NFKB inhibitor alpha | Bos taurus |
| 9 | The data presented here demonstrate that activation of NOD1/NF-kappaB pathway contributes to the functional responses of neutrophils to cLPS. | cryptolepine | nucleotide binding oligomerization domain containing 1 | Bos taurus |
| 10 | The data presented here demonstrate that activation of NOD1/NF-kappaB pathway contributes to the functional responses of neutrophils to cLPS. | cryptolepine | nuclear factor kappa B subunit 1 | Homo sapiens |