Title : Cross-talk between α7 nAChR-mediated cholinergic pathway and acylation stimulating protein signaling in 3T3-L1 adipocytes: role of NFκB and STAT3.

Pub. Date : 2015 Aug

PMID : 25985797






8 Functional Relationships(s)
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1 Our results show that preincubation of 3T3-L1 cells with alpha7nAChR agonist GTS-21 significantly reduces ASP-mediated chemokine MCP-1 secretion, which is regulated though nuclear factor kappaB (NFkappaB) and signal transducer and activator of transcription 3 (STAT3). 3-(2,4-dimethoxybenzylidene)anabaseine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Our results show that preincubation of 3T3-L1 cells with alpha7nAChR agonist GTS-21 significantly reduces ASP-mediated chemokine MCP-1 secretion, which is regulated though nuclear factor kappaB (NFkappaB) and signal transducer and activator of transcription 3 (STAT3). 3-(2,4-dimethoxybenzylidene)anabaseine mast cell protease 1 Mus musculus
3 Our results show that preincubation of 3T3-L1 cells with alpha7nAChR agonist GTS-21 significantly reduces ASP-mediated chemokine MCP-1 secretion, which is regulated though nuclear factor kappaB (NFkappaB) and signal transducer and activator of transcription 3 (STAT3). 3-(2,4-dimethoxybenzylidene)anabaseine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
4 Our results show that preincubation of 3T3-L1 cells with alpha7nAChR agonist GTS-21 significantly reduces ASP-mediated chemokine MCP-1 secretion, which is regulated though nuclear factor kappaB (NFkappaB) and signal transducer and activator of transcription 3 (STAT3). 3-(2,4-dimethoxybenzylidene)anabaseine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
5 Our results show that preincubation of 3T3-L1 cells with alpha7nAChR agonist GTS-21 significantly reduces ASP-mediated chemokine MCP-1 secretion, which is regulated though nuclear factor kappaB (NFkappaB) and signal transducer and activator of transcription 3 (STAT3). 3-(2,4-dimethoxybenzylidene)anabaseine signal transducer and activator of transcription 3 Mus musculus
6 Our results show that preincubation of 3T3-L1 cells with alpha7nAChR agonist GTS-21 significantly reduces ASP-mediated chemokine MCP-1 secretion, which is regulated though nuclear factor kappaB (NFkappaB) and signal transducer and activator of transcription 3 (STAT3). 3-(2,4-dimethoxybenzylidene)anabaseine signal transducer and activator of transcription 3 Mus musculus
7 Treatment of 3T3-L1 cells with GTS-21 significantly reduced NFkappaB activation by DNA binding and STAT3 activation by disturbing post-translational modification. 3-(2,4-dimethoxybenzylidene)anabaseine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
8 Treatment of 3T3-L1 cells with GTS-21 significantly reduced NFkappaB activation by DNA binding and STAT3 activation by disturbing post-translational modification. 3-(2,4-dimethoxybenzylidene)anabaseine signal transducer and activator of transcription 3 Mus musculus