Title : Ceramide production mediates cinobufotalin-induced growth inhibition and apoptosis in cultured hepatocellular carcinoma cells.

Pub. Date : 2015 Aug

PMID : 25724183






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Ceramide synthase-1 small hairpin RNA (shRNA)-depletion inhibited cinobufotalin-induced ceramide production and HCC cell apoptosis. cinobufotalin ceramide synthase 1 Homo sapiens
2 Ceramide synthase-1 small hairpin RNA (shRNA)-depletion inhibited cinobufotalin-induced ceramide production and HCC cell apoptosis. Ceramides ceramide synthase 1 Homo sapiens
3 Finally, we observed that cinobufotalin inactivated Akt-S6K1 signaling in HepG2 cells, which was again inhibited by ceramide synthase-1 shRNA-depletion. cinobufotalin ceramide synthase 1 Homo sapiens