Title : Gastrodin ameliorates depressive-like behaviors and up-regulates the expression of BDNF in the hippocampus and hippocampal-derived astrocyte of rats.

Pub. Date : 2014 Jan

PMID : 24293261






3 Functional Relationships(s)
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1 Gastrodin ameliorates depressive-like behaviors and up-regulates the expression of BDNF in the hippocampus and hippocampal-derived astrocyte of rats. gastrodin brain-derived neurotrophic factor Rattus norvegicus
2 Increased levels of ERK1/2 phosphorylation and BDNF protein were also observed after GAS (20 mug/mL) treatment for 72 h. These results indicate that gastrodin possesses antidepressant effect. gastrodin mitogen activated protein kinase 3 Rattus norvegicus
3 Increased levels of ERK1/2 phosphorylation and BDNF protein were also observed after GAS (20 mug/mL) treatment for 72 h. These results indicate that gastrodin possesses antidepressant effect. gastrodin brain-derived neurotrophic factor Rattus norvegicus