Pub. Date : 2013 Oct 15
PMID : 24084256
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). | Dioxins | aryl hydrocarbon receptor 2 | Danio rerio |
| 2 | The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). | Polychlorinated Biphenyls | aryl hydrocarbon receptor 2 | Danio rerio |
| 3 | The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). | Polychlorinated Biphenyls | aryl hydrocarbon receptor 2 | Danio rerio |
| 4 | The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). | Polycyclic Aromatic Hydrocarbons | aryl hydrocarbon receptor 2 | Danio rerio |
| 5 | The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). | Polycyclic Aromatic Hydrocarbons | aryl hydrocarbon receptor 2 | Danio rerio |
| 6 | As has been shown previously, knockdown of AHR2 resulted in protection from PAH- and PCB-induced cardiac deformities and prevented CYP1 enzyme activity in exposed embryos. | Polycyclic Aromatic Hydrocarbons | aryl hydrocarbon receptor 2 | Danio rerio |
| 7 | As has been shown previously, knockdown of AHR2 resulted in protection from PAH- and PCB-induced cardiac deformities and prevented CYP1 enzyme activity in exposed embryos. | Polychlorinated Biphenyls | aryl hydrocarbon receptor 2 | Danio rerio |
| 8 | In contrast, co-knockdown of AHR1A and AHR2 did protect from PCB-126-induced deformities. | 3,3',4,4',5-Pentachlorobiphenyl | aryl hydrocarbon receptor 2 | Danio rerio |