PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24084256-0 2013 Knockdown of AHR1A but not AHR1B exacerbates PAH and PCB-126 toxicity in zebrafish (Danio rerio) embryos. Polycyclic Aromatic Hydrocarbons 45-48 aryl hydrocarbon receptor 1a Danio rerio 13-18 24084256-0 2013 Knockdown of AHR1A but not AHR1B exacerbates PAH and PCB-126 toxicity in zebrafish (Danio rerio) embryos. Polychlorinated Biphenyls 53-56 aryl hydrocarbon receptor 1a Danio rerio 13-18 24084256-3 2013 The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). Dioxins 220-227 aryl hydrocarbon receptor 2 Danio rerio 124-128 24084256-3 2013 The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). Polychlorinated Biphenyls 229-254 aryl hydrocarbon receptor 2 Danio rerio 124-128 24084256-3 2013 The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). Polychlorinated Biphenyls 256-260 aryl hydrocarbon receptor 2 Danio rerio 124-128 24084256-3 2013 The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). Polycyclic Aromatic Hydrocarbons 267-299 aryl hydrocarbon receptor 2 Danio rerio 124-128 24084256-3 2013 The zebrafish (Danio rerio) has three identified AHRs: AHR1A and AHR1B, the roles of which are not yet well elucidated, and AHR2, which has been shown to mediate the toxicity of various anthropogenic compounds including dioxins, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). Polycyclic Aromatic Hydrocarbons 301-305 aryl hydrocarbon receptor 2 Danio rerio 124-128 24084256-4 2013 In this study, we sought to explore the role of the two AHR1 isoforms in PAH- and PCB-induced toxicity in zebrafish embryos utilizing morpholino gene knockdown of the AHR isoforms. Polycyclic Aromatic Hydrocarbons 73-76 aryl hydrocarbon receptor 1a Danio rerio 56-60 24084256-4 2013 In this study, we sought to explore the role of the two AHR1 isoforms in PAH- and PCB-induced toxicity in zebrafish embryos utilizing morpholino gene knockdown of the AHR isoforms. Polycyclic Aromatic Hydrocarbons 73-76 aryl hydrocarbon receptor 1a Danio rerio 56-59 24084256-4 2013 In this study, we sought to explore the role of the two AHR1 isoforms in PAH- and PCB-induced toxicity in zebrafish embryos utilizing morpholino gene knockdown of the AHR isoforms. Polychlorinated Biphenyls 82-85 aryl hydrocarbon receptor 1a Danio rerio 56-60 24084256-4 2013 In this study, we sought to explore the role of the two AHR1 isoforms in PAH- and PCB-induced toxicity in zebrafish embryos utilizing morpholino gene knockdown of the AHR isoforms. Polychlorinated Biphenyls 82-85 aryl hydrocarbon receptor 1a Danio rerio 56-59 24084256-5 2013 Knockdown of AHR1B did not affect the toxicity of PAH mixtures or PCB-126, whereas knockdown of AHR1A exacerbated the cardiac toxicity caused by PAH mixtures and PCB-126. Polycyclic Aromatic Hydrocarbons 145-148 aryl hydrocarbon receptor 1a Danio rerio 96-101 24084256-5 2013 Knockdown of AHR1B did not affect the toxicity of PAH mixtures or PCB-126, whereas knockdown of AHR1A exacerbated the cardiac toxicity caused by PAH mixtures and PCB-126. Polychlorinated Biphenyls 162-165 aryl hydrocarbon receptor 1a Danio rerio 96-101 24084256-7 2013 As has been shown previously, knockdown of AHR2 resulted in protection from PAH- and PCB-induced cardiac deformities and prevented CYP1 enzyme activity in exposed embryos. Polycyclic Aromatic Hydrocarbons 76-79 aryl hydrocarbon receptor 2 Danio rerio 43-47 24084256-7 2013 As has been shown previously, knockdown of AHR2 resulted in protection from PAH- and PCB-induced cardiac deformities and prevented CYP1 enzyme activity in exposed embryos. Polychlorinated Biphenyls 85-88 aryl hydrocarbon receptor 2 Danio rerio 43-47 24084256-9 2013 In contrast, co-knockdown of AHR1A and AHR2 did protect from PCB-126-induced deformities. 3,3',4,4',5-Pentachlorobiphenyl 61-68 aryl hydrocarbon receptor 1a Danio rerio 29-34 24084256-9 2013 In contrast, co-knockdown of AHR1A and AHR2 did protect from PCB-126-induced deformities. 3,3',4,4',5-Pentachlorobiphenyl 61-68 aryl hydrocarbon receptor 2 Danio rerio 39-43