Title : Determination of oxycodone, noroxycodone and oxymorphone by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry in human matrices: in vivo and in vitro applications.

Pub. Date : 2013 Jul-Aug

PMID : 23743505






2 Functional Relationships(s)
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1 With a panel of recombinant human cytochrome P450s (CYPs), CYP2C18 and CYP3A4 produced the most noroxycodone, whereas CYP2D6 produced the most oxymorphone. noroxycodone cytochrome P450 family 2 subfamily C member 18 Homo sapiens
2 With a panel of recombinant human cytochrome P450s (CYPs), CYP2C18 and CYP3A4 produced the most noroxycodone, whereas CYP2D6 produced the most oxymorphone. Oxymorphone cytochrome P450 family 2 subfamily C member 18 Homo sapiens