Pub. Date : 2011 Dec
PMID : 21983642
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The overproduction and mRNA expression of TNF-alpha, IL-1beta and IL-6 were remarkably suppressed in serum and synovium tissue of all TCDCA-treated rats, however, IL-10 was markedly increased in prophylactic treatment. | Taurochenodeoxycholic Acid | tumor necrosis factor | Rattus norvegicus |
| 2 | The overproduction and mRNA expression of TNF-alpha, IL-1beta and IL-6 were remarkably suppressed in serum and synovium tissue of all TCDCA-treated rats, however, IL-10 was markedly increased in prophylactic treatment. | Taurochenodeoxycholic Acid | interleukin 1 beta | Rattus norvegicus |
| 3 | The overproduction and mRNA expression of TNF-alpha, IL-1beta and IL-6 were remarkably suppressed in serum and synovium tissue of all TCDCA-treated rats, however, IL-10 was markedly increased in prophylactic treatment. | Taurochenodeoxycholic Acid | interleukin 6 | Rattus norvegicus |
| 4 | The overproduction and mRNA expression of TNF-alpha, IL-1beta and IL-6 were remarkably suppressed in serum and synovium tissue of all TCDCA-treated rats, however, IL-10 was markedly increased in prophylactic treatment. | Taurochenodeoxycholic Acid | interleukin 10 | Rattus norvegicus |
| 5 | In a definite concentration ranging from 300 mug/mL to 500 mug/mL, TCDCA showed marked inhibition in the overproduction and mRNA expression of TNF-alpha, IL-1beta and IL-6 in synoviocytes in a concentration-dependent manner, but opposite action on IL-10. | Taurochenodeoxycholic Acid | tumor necrosis factor | Rattus norvegicus |
| 6 | In a definite concentration ranging from 300 mug/mL to 500 mug/mL, TCDCA showed marked inhibition in the overproduction and mRNA expression of TNF-alpha, IL-1beta and IL-6 in synoviocytes in a concentration-dependent manner, but opposite action on IL-10. | Taurochenodeoxycholic Acid | interleukin 1 beta | Rattus norvegicus |
| 7 | In a definite concentration ranging from 300 mug/mL to 500 mug/mL, TCDCA showed marked inhibition in the overproduction and mRNA expression of TNF-alpha, IL-1beta and IL-6 in synoviocytes in a concentration-dependent manner, but opposite action on IL-10. | Taurochenodeoxycholic Acid | interleukin 6 | Rattus norvegicus |
| 8 | In a definite concentration ranging from 300 mug/mL to 500 mug/mL, TCDCA showed marked inhibition in the overproduction and mRNA expression of TNF-alpha, IL-1beta and IL-6 in synoviocytes in a concentration-dependent manner, but opposite action on IL-10. | Taurochenodeoxycholic Acid | interleukin 10 | Rattus norvegicus |
| 9 | In conclusion, treatment with TCDCA confers a good anti-adjuvant arthritis activity in rats, which its reparative effects could be mediated via reduction of the protein and mRNA expression of TNF-alpha, IL-1beta and IL-6, and augment of IL-10 in rats. | Taurochenodeoxycholic Acid | tumor necrosis factor | Rattus norvegicus |
| 10 | In conclusion, treatment with TCDCA confers a good anti-adjuvant arthritis activity in rats, which its reparative effects could be mediated via reduction of the protein and mRNA expression of TNF-alpha, IL-1beta and IL-6, and augment of IL-10 in rats. | Taurochenodeoxycholic Acid | interleukin 1 beta | Rattus norvegicus |
| 11 | In conclusion, treatment with TCDCA confers a good anti-adjuvant arthritis activity in rats, which its reparative effects could be mediated via reduction of the protein and mRNA expression of TNF-alpha, IL-1beta and IL-6, and augment of IL-10 in rats. | Taurochenodeoxycholic Acid | interleukin 6 | Rattus norvegicus |
| 12 | In conclusion, treatment with TCDCA confers a good anti-adjuvant arthritis activity in rats, which its reparative effects could be mediated via reduction of the protein and mRNA expression of TNF-alpha, IL-1beta and IL-6, and augment of IL-10 in rats. | Taurochenodeoxycholic Acid | interleukin 10 | Rattus norvegicus |