Title : Hydroquinone stimulates inflammatory functions in microvascular endothelial cells via NF-κB nuclear activation.

Pub. Date : 2011 Nov

PMID : 21645265






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Hydroquinone treatment induced the membrane expression of cell adhesion molecules (CAMs) from the immunoglobulin superfamilies ICAM-1 (intercellular), VCAM-1(vascular) and PECAM-1 (platelet endothelial) and induced the secretion of cytokines interleukin-1beta (IL-1beta) and tumour necrosis factor-alpha (TNF-alpha). hydroquinone platelet and endothelial cell adhesion molecule 1 Rattus norvegicus
2 In addition, the incubation of endothelial cells with benzoquinone (10 muM, 2 hr) impaired PECAM-1 expression and did not modify NF-kappaB nuclear activation. quinone platelet and endothelial cell adhesion molecule 1 Rattus norvegicus