Pub. Date : 2011 Feb
PMID : 21428211
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Silencing of Bmi-1 gene by RNA interference enhances sensitivity to doxorubicin in breast cancer cells. | Doxorubicin | BMI1 proto-oncogene, polycomb ring finger | Homo sapiens |
| 2 | The results obtained indicated that silencing of Bmi-1 can render MCF-7 cells more sensitive to doxorubicin which induced a significantly higher percentage of apoptosis cells in vitro and in vivo. | Doxorubicin | BMI1 proto-oncogene, polycomb ring finger | Homo sapiens |
| 3 | All together these results clearly demonstrate that Bmi-1 siliencing combined treatment of doxorubicin might be a new strategy for biological treatment on breast cancer. | Doxorubicin | BMI1 proto-oncogene, polycomb ring finger | Homo sapiens |