Title : Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability.

Pub. Date : 2010 Jun 29

PMID : 20614016






1 Functional Relationships(s)
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1 Structural modeling, enrichment of CsA-binding proteins from parasite extracts by FPLC, and PPIase activity assays revealed direct interaction of the inhibitor with LmaCyP40, a bifunctional cyclophilin with potential co-chaperone function. lmacyp40 FKBP prolyl isomerase 1B Homo sapiens