Protein Name | FKBP prolyl isomerase 1B |
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Organism | Homo sapiens |
Gene ID | 2281 |
Gene Symbol | FKBP1B |
UniProt | P68106 (FKB1B_HUMAN), F8W6G9 (F8W6G9_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
64
Total Number of Articles : 61 |
Description |
FKBP prolyl isomerase 1B |
Gene Summary |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008] |
synonyms |
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Properties | |