Title : Nootkatone, a characteristic constituent of grapefruit, stimulates energy metabolism and prevents diet-induced obesity by activating AMPK.

Pub. Date : 2010 Aug

PMID : 20501876






2 Functional Relationships(s)
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1 Nootkatone-induced activation of AMPK was possibly mediated both by LKB1 and Ca(2+)/calmodulin-dependent protein kinase kinase. nootkatone serine/threonine kinase 11 Mus musculus
2 In addition, administration of nootkatone (200 mg/kg body wt) significantly enhanced AMPK activity, accompanied by LKB1, AMPK, and ACC phosphorylation in the liver and muscle of mice. nootkatone serine/threonine kinase 11 Mus musculus