Title : The enzymatic activity of human cytotoxic T-lymphocyte granzyme A and cytolysis mediated by cytotoxic T-lymphocytes are potently inhibited by a synthetic antiprotease, FUT-175.

Pub. Date : 1991 Jan

PMID : 1989498






3 Functional Relationships(s)
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1 The synthetic antiprotease, FUT-175 (6-amidino-2-naphthyl-4-guanidinobenzoate), was found to be an extraordinarily potent and rapid inhibitor of human Q31 cytotoxic T-lymphocyte granzyme A. fut granzyme A Homo sapiens
2 The synthetic antiprotease, FUT-175 (6-amidino-2-naphthyl-4-guanidinobenzoate), was found to be an extraordinarily potent and rapid inhibitor of human Q31 cytotoxic T-lymphocyte granzyme A. nafamostat granzyme A Homo sapiens
3 Four other FUT-175 analogs were also found to be potent, rapid Q31 granzyme A inhibitors. fut granzyme A Homo sapiens