Protein Name granzyme A
Organism Homo sapiens
Gene ID 3001
Gene Symbol


UniProt P12544 (GRAA_HUMAN)
Relationships Total Number of functionally related compound(s) : 64
Total Number of Articles : 64

granzyme A

Gene Summary

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008]

  • granzyme A
  • CTL tryptase
  • Cytotoxic T-lymphocyte-associated serine esterase-3
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