Pub. Date : 2009 Nov
PMID : 19675145
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Gene expression analysis revealed that TCDD caused a dose-dependent suppression of Igmicro chain, Igkappa chain, IgJ chain, XBP-1, and Blimp-1. | Polychlorinated Dibenzodioxins | PR domain containing 1, with ZNF domain | Mus musculus |
| 2 | TCDD also dose-dependently suppressed LPS-stimulated increases in Blimp-1 protein expression in CD19+ B cells. | Polychlorinated Dibenzodioxins | PR domain containing 1, with ZNF domain | Mus musculus |
| 3 | TCDD also dose-dependently suppressed LPS-stimulated increases in Blimp-1 protein expression in CD19+ B cells. | lps | PR domain containing 1, with ZNF domain | Mus musculus |
| 4 | The deregulation of Blimp-1 expression by TCDD provides a partial explanation for the concomitant suppression of the IgM response and confirms previous observations established in vitro. | Polychlorinated Dibenzodioxins | PR domain containing 1, with ZNF domain | Mus musculus |