Protein Name PR domain containing 1, with ZNF domain
Organism Mus musculus
Gene ID 12142
Gene Symbol

Prdm1

UniProt Q60636 (PRDM1_MOUSE)
Relationships Total Number of functionally related compound(s) : 63
Total Number of Articles : 57
Description

PR domain containing 1, with ZNF domain

Gene Summary

Enables histone methyltransferase binding activity; promoter-specific chromatin binding activity; and transcription cis-regulatory region binding activity. Involved in gene expression; peptidyl-arginine methylation; and regulation of lymphocyte differentiation. Acts upstream of or within several processes, including circulatory system development; eye morphogenesis; and regulation of gene expression. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; retina; and skin. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and lung adenocarcinoma. Orthologous to human PRDM1 (PR/SET domain 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • PR domain zinc finger protein 1
  • B lymphocyte induced maturation protein
  • B lymphocyte-induced maturation protein 1
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Properties