Title : Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells.

Pub. Date : 2009 Mar

PMID : 19212692






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1 In the present study, we investigated the potential mechanisms underlying the anti-angiogenic effect exerted by the potent PARP inhibitor GPI 15427, analyzing gene expression in human endothelial cells shortly after treatment with this compound. GPI 15427 poly(ADP-ribose) polymerase 1 Homo sapiens