Title : GANP suppresses the arginine methyltransferase PRMT5 regulating IL-4-mediated STAT6-signaling to IgE production in B cells.

Pub. Date : 2009 Mar

PMID : 19181385






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 GANP down-regulates JAK1/JAK3 to STAT6-signaling with regulation of arginine methylation activity, which might be responsible for the B cell endogenous suppressive mechanism of hyper-IgE. Arginine Janus kinase 1 Mus musculus