Title : The angiotensin-calcineurin-NFAT pathway mediates stretch-induced up-regulation of matrix metalloproteinases-2/-9 in atrial myocytes.

Pub. Date : 2009 Jul

PMID : 19148693






2 Functional Relationships(s)
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1 Losartan, CsA or VIV abolished stretch-induced alterations in MMP-2/-9 and MT1-MMP expression and enzyme activity by normalizing the Cn-activity and the DNA binding activity of NFATc1. Losartan matrix metallopeptidase 14 Rattus norvegicus
2 Losartan, CsA or VIV abolished stretch-induced alterations in MMP-2/-9 and MT1-MMP expression and enzyme activity by normalizing the Cn-activity and the DNA binding activity of NFATc1. Cyclosporine matrix metallopeptidase 14 Rattus norvegicus