| Protein Name | matrix metallopeptidase 14 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 81707 |
| Gene Symbol | Mmp14 |
| UniProt | Q10739 (MMP14_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
49
Total Number of Articles : 45 |
Description |
matrix metallopeptidase 14 |
| Gene Summary |
Enables integrin binding activity. Involved in several processes, including cellular response to genistein; gonad development; and negative regulation of focal adhesion assembly. Predicted to be located in several cellular components, including cytosol; intermediate filament cytoskeleton; and macropinosome. Predicted to be active in extracellular space and plasma membrane. Used to study ischemia. Biomarker of IgA glomerulonephritis; anti-basement membrane glomerulonephritis; artery disease (multiple); cerebrovascular disease (multiple); and congestive heart failure. Human ortholog(s) of this gene implicated in Winchester syndrome; esophagus adenocarcinoma; and myocardial infarction. Orthologous to human MMP14 (matrix metallopeptidase 14). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |