Title : Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.

Pub. Date : 2009 Jan 1

PMID : 18789002






1 Functional Relationships(s)
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1 Human colon cancer cells and primary colon cancer silence the gene coding for LDH (lactate dehydrogenase)-B and up-regulate the gene coding for LDH-A, resulting in effective conversion of pyruvate into lactate. Pyruvic Acid lactate dehydrogenase B Homo sapiens