Title : Retrieval of the rat canalicular conjugate export pump Mrp2 is associated with a rearrangement of actin filaments and radixin in bile salt-induced cholestasis.

Pub. Date : 2008 Jul 28

PMID : 18700187






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 We have studied the effects of TCDCA on the distribution of Mrp2 and P-glycoproteins with respect to changes in the actin cytoskeleton and actin associated proteins radixin and ZO-1. Taurochenodeoxycholic Acid ATP binding cassette subfamily C member 2 Rattus norvegicus
2 We have studied the effects of TCDCA on the distribution of Mrp2 and P-glycoproteins with respect to changes in the actin cytoskeleton and actin associated proteins radixin and ZO-1. Taurochenodeoxycholic Acid tight junction protein 1 Rattus norvegicus
3 TCDCA at subcholestatic amounts (0.1 micromol/min/100 g body weight) led to distortion and dilation of the canaliculi which was apparent in actin, ZO-1, and Mrp2 fluorescence. Taurochenodeoxycholic Acid tight junction protein 1 Rattus norvegicus
4 TCDCA at subcholestatic amounts (0.1 micromol/min/100 g body weight) led to distortion and dilation of the canaliculi which was apparent in actin, ZO-1, and Mrp2 fluorescence. Taurochenodeoxycholic Acid ATP binding cassette subfamily C member 2 Rattus norvegicus