Title : The ubiquitin-mediated degradation of Jak1 modulates osteoclastogenesis by limiting interferon-beta-induced inhibitory signaling.

Pub. Date : 2008 Jan 15

PMID : 17928529






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 RANKL induced Jak1 ubiquitination, and a proteasome inhibitor MG132 efficiently blocked the RANKL-induced degradation of Jak1. benzyloxycarbonylleucyl-leucyl-leucine aldehyde Janus kinase 1 Mus musculus
2 RANKL induced Jak1 ubiquitination, and a proteasome inhibitor MG132 efficiently blocked the RANKL-induced degradation of Jak1. benzyloxycarbonylleucyl-leucyl-leucine aldehyde Janus kinase 1 Mus musculus