| Protein Name | Bcl2-like 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24888 |
| Gene Symbol | Bcl2l1 |
| UniProt | P53563 (B2CL1_RAT), Q7TS62 (Q7TS62_RAT), Q548R7 (Q548R7_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
299
Total Number of Articles : 358 |
Description |
Bcl2-like 1 |
| Gene Summary |
Enables several functions, including GTPase binding activity; MDM2/MDM4 family protein binding activity; and cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of transport; and regulation of apoptotic process. Located in bounding membrane of organelle; clathrin-coated pit; and cytosol. Is active in synaptic vesicle. Used to study amyotrophic lateral sclerosis; artery disease (multiple); endometriosis; gastric ulcer; and impotence. Biomarker of several diseases, including acute kidney failure; brain ischemia; hepatocellular carcinoma; ocular hypertension; and status epilepticus. Human ortholog(s) of this gene implicated in breast cancer; carcinoma (multiple); leukemia (multiple); and pancreatic cancer. Orthologous to human BCL2L1 (BCL2 like 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |