Title : Effects of dietary corn bran hemicellulose and neomycin on hepatic caspase-3 activity and glycoprotein concentration in rats treated with or without D-galactosamine.

Pub. Date : 2006 Apr

PMID : 16802689






2 Functional Relationships(s)
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1 At 6 h, hepatic caspase-3 activity was elevated by CBH diet alone as high as that of the GalN-injected control-diet group, and the activity was not elevated further by GalN. S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE caspase 3 Rattus norvegicus
2 These results suggest that dietary CBH elevates hepatic caspase-3 activity and reduces hepatic glycoprotein concentration, and may imply that CBH would suppress GalN-hepatitis not at the early- or middle-step of apoptosis but at the late-step of apoptosis or necrosis, although the relation between these phenomena and the alleviative effects of CBH and Neo on GalN-induced hepatitis is yet to be clarified. S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE caspase 3 Rattus norvegicus