Pub. Date : 2007 Feb-Mar
PMID : 16698078
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Urocortin (UCN) is a 40 amino acid peptide which is closely related to corticotropin-releasing hormone and binds with high affinity to both CRH type 1 and type 2 receptors. | Urocortins | urocortin | Homo sapiens |
| 2 | This study was designed to investigate the cellular localization of UCN at the implantation site of the human blastocyst, as well as the regulation of the UCN promoter by two major intracellular signaling pathways, the cAMP/PKA and diacylglycerol/PKC pathways, in cells of placental origin. | Cyclic AMP | urocortin | Homo sapiens |
| 3 | This study was designed to investigate the cellular localization of UCN at the implantation site of the human blastocyst, as well as the regulation of the UCN promoter by two major intracellular signaling pathways, the cAMP/PKA and diacylglycerol/PKC pathways, in cells of placental origin. | Diglycerides | urocortin | Homo sapiens |
| 4 | Immunohistochemistry revealed expression of UCN in the cytotrophoblast, the EVT and decidual cells. | EVT | urocortin | Homo sapiens |
| 5 | Both UCN mRNA and peptide were detectable in freshly isolated EVT. | EVT | urocortin | Homo sapiens |
| 6 | Finally, a human UCN promoter luciferase reporter construct transfected into JEG3 cells was significantly inducible by phorbol ester plus ionomycin, but not by phorbol ester alone or by forskolin. | Phorbol Esters | urocortin | Homo sapiens |
| 7 | Finally, a human UCN promoter luciferase reporter construct transfected into JEG3 cells was significantly inducible by phorbol ester plus ionomycin, but not by phorbol ester alone or by forskolin. | Ionomycin | urocortin | Homo sapiens |
| 8 | Finally, a human UCN promoter luciferase reporter construct transfected into JEG3 cells was significantly inducible by phorbol ester plus ionomycin, but not by phorbol ester alone or by forskolin. | Phorbol Esters | urocortin | Homo sapiens |
| 9 | Collectively, the present study reports the expression of UCN in EVT and the activation of the UCN gene promoter by the diacylglycerol/PKC pathway. | EVT | urocortin | Homo sapiens |
| 10 | Collectively, the present study reports the expression of UCN in EVT and the activation of the UCN gene promoter by the diacylglycerol/PKC pathway. | Diglycerides | urocortin | Homo sapiens |
| 11 | Collectively, the present study reports the expression of UCN in EVT and the activation of the UCN gene promoter by the diacylglycerol/PKC pathway. | Diglycerides | urocortin | Homo sapiens |
| 12 | The functional significance of urocortin for the physiology of EVT requires further investigation. | EVT | urocortin | Homo sapiens |