Title : Cutting edge: apoptosis-regulating signal kinase 1 is required for reactive oxygen species-mediated activation of IFN regulatory factor 3 by lipopolysaccharide.

Pub. Date : 2006 May 15

PMID : 16670275






1 Functional Relationships(s)
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1 Furthermore, we present evidence that LPS-mediated ROS production leads to activation of apoptosis-regulating-signal kinase (ASK) 1, a MAPK kinase kinase family member capable of activating the MAP kinase 6/p38 axis. Reactive Oxygen Species mitogen-activated protein kinase kinase kinase 5 Homo sapiens