Title : Mechanism of cyclooxygenase-2 upregulation in late preconditioning.

Pub. Date : 2003 May

PMID : 12738234






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We conclude that (i) the upregulation of COX-2 protein expression after ischemic PC is mediated by a JAK1/2-STAT1/3-signaling cascade; (ii) COX-2 activity requires upregulated iNOS and iNOS-derived NO; and (iii) COX-2 forms complexes with iNOS, supporting a direct interaction between these two proteins. pc Janus kinase 1 Mus musculus